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- ...responsible for a previously unrecognized homeostatic endocrine feed-back regulation of the central vagal system including appetite and energy homeostasis. Your project will aim at establishing novel means to improve not only the efficacy but, importantly also the...
- ...is broadly interested in how neuronal, hormonal, nutrient, and bioenergetic signalling pathways collectively orchestrate systemic energy homeostasis and defend metabolic health. We explore coordination between peripheral and central homeostatic pathways through a combinatorial...
- ...aim to uncover how adipose tissue communicates with other organs to regulate whole-body metabolism. While traditionally viewed as an energy reservoir and mechanical cushion, adipose tissue is now recognized as a key endocrine organ essential for maintaining systemic...
- ...that regulate body weight. Our research focuses on identifying key physiological and molecular pathways that regulate food intake and energy expenditure. In context, a major area of interest in our lab is understanding how changes in energy balance influence...
- ...disciplines. Our Research The overarching aim of the Sakamoto Group is to elucidate molecular mechanisms governing cellular energy sensing and the maintenance of metabolic homeostasis, with the ultimate aim of identifying and validating therapeutic candidates...