Principal ADME Scientist

Development ADME

Måløv, Copenhagen area, Denmark

Are you an experienced ADME (Absorption, distribution, metabolism and excretion) scientist with drug-drug interaction (DDI) expertise? Do you want to ensure scientific and strategic excellence within ADME and DDI in drug development projects? If so, apply today and join Development ADME in a permanent principal scientist position within the Research and Development organisation at Novo Nordisk.

Your new role As a Principal ADME Scientist, you will be responsible for evaluating ADME and DDI risks and strategies from late-stage discovery through non-clinical and clinical development to regulatory submission. Working across a diverse portfolio, you will provide scientific leadership on ADME- and DDI-related questions, support key project decisions, and contribute to advancing programmes throughout drug development.

  Some of your main responsibilities will include:

• Design, conduct, and interpret in vitro and in vivo studies to evaluate ADME and DDI profiles of drug candidates across modalities (small molecules, peptides and biologics) both in-house and with contract research organisations (CROs)
• Inform and guide projects on ADME- and DDI-related topics
• Interacting with regulatory authorities, including providing written input to regulatory documents (e.g. IB, IND, IMPD, BLA, NDA)
• Champion innovation and new scientific initiatives for early and late-stage development programs by proactively reviewing literature and other technological advancements in the scientific area
• Interpret and translate results and put them into the appropriate scientific context to support sound project decisions
• Independently identify, analyse, and resolve unique and complex scientific and strategic challenges that may have a broad impact on the project portfolio
• Communicate complex scientific data, conclusions, and recommendations clearly to stakeholders with diverse scientific and professional backgrounds

Your new department
In Development ADME, we are responsible for evaluation of drug disposition, metabolism and excretion and DDI from late-stage discovery, throughout non-clinical and clinical development towards drug registration. We work with several stakeholders within R&D and conduct different types of ADME, and DDI studies to support the drug safety evaluation, regulatory submissions, and the drug label.

You will be part of a team, which consist of scientists and laboratory technicians: all highly skilled and dedicated people working together in an open and scientifically challenging environment. We are open-minded and value collaboration, scientific discussions, and knowledge-sharing.

 
Your skills & qualifications

To succeed in the role, you have:  

• Ph.D. is preferred or Master’s degree within pharmaceutical or medical sciences or equivalent area
• Several years of relevant experience within ADME and ideally DDI in drug development in the pharmaceutical/biotech industry
• Flair for and solid experience with bioanalytical and/or mass spectrometric approaches for characterisation and quantification of drug candidates and metabolites
• Solid experience with ADME and DDI study conduct
• Demonstrated knowledge of interpretation and translation of results from in vitro, ex vivo, and in vivo ADME, and DDI studies
• Outstanding ability to identify challenges, develop strategies, and translate them into relevant study designs
• Experience with due diligence evaluation within ADME and DDI is an advantage
• Strong understanding of scientific and strategic principles of drug development

As a person, you are open-minded, keen to learn new skills and able to communicate with experts in other areas. You have exceptional communication and stakeholder management skills and the ability to effectively interact with colleagues with a variety of backgrounds. Furthermore, you have demonstrated experience and a keen interest in mentoring and sharing knowledge with junior scientists and colleagues.

What we offer

At Novo Nordisk, you’ll join a global healthcare company with a unique culture and strong results. We offer continuous learning, career development, and benefits tailored to your life and career stage.

Salary:   For this role, the Annual B ase S alary ranges from 742,600.00 to 1,091,600.00 DKK, corresponding to the level of the position.

The placement within the salary range will be assessed during the recruitment process based on the candidate’s skills, competencies, knowledge, and relevant experience.

Incentives and Benefits: The salary package may include short-term and/or long-term incentives as well as other employee benefits based on position level, location, functional area and relevant market benchmarks.

Learn more about our Reward Philosophy her e .

More information
For further information about the position please contact Martha Kampp Nøhr Vestergaard, Assoc Director of Development ADME on Vis telefonnummer.

Deadline  27 September 2026.

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

At Novo Nordisk, we're not chasing quick fixes – we're creating lasting change for long-term health. For over 100 years, we've been driven by a single purpose: to defeat serious chronic diseases and help millions of people live healthier lives. This dedication fuels our constant curiosity and inspires us to push the boundaries of what's possible in healthcare. We embrace diverse perspectives, seek out bold ideas, and build partnerships rooted in shared purpose. Together, we're making healthcare more accessible, treating and preventing diseases, and pioneering solutions that create change spanning generations. When you join us, you become part of something bigger – a legacy of impact that reaches far beyond today.